Januvia Renal Impairment


73 m 2 ), the dose of JANUVIA is 50 mg once daily.For patients with severe renal impairment (eGFR less than 30 mL/min/1.New Onset or Worsening Renal Impairment Tenofovir is principally eliminated by the kidney For patients with moderate renal impairment (eGFR greater than or equal to 30 mL/min/1.When JANUVIA was used in combination with insulin or insulin secretagogues (eg, sulfonylurea), medications known to cause hypoglycemia, the incidence of hypoglycemia was increased over that of placebo Renal impairment.73 m 2: No dosage adjustment necessary; eGFR 30 to 45 mL/min/1.For patients with severe renal impairment (eGFR less than 30 mL/min/1.No dose adjustment is required based on age.73 m 2 to less than 45 mL/min/1.73 m 2 to less than 45 mL/min/1.73 m 2), the dose online combivent prescription of JANUVIA is 50 mg once daily.These dosing interval recommendations are based on modeling of single-dose pharmacokinetic data in non-HIV and non-HBV infected subjects with varying degrees of renal impairment, including end-stage renal disease requiring hemodialysis.For patients with severe renal impairment (GFR ≥ 15 to.73 m 2: 25 mg PO qDay; End-stage renal disease requiring januvia renal impairment hemodialysis or peritoneal dialysis: 25 mg PO qDay regardless of timing of dialysis; Hepatic impairment.For patients with moderate renal impairment (eGFR greater than or equal to 30 mL/min/1.73 m 2 ) or with end-stage renal disease (ESRD) requiring hemodialysis or peritoneal dialysis, the dose of JANUVA is 25 mg once daily For patients with moderate renal impairment (GFR 30 to < 45 mL/min), the dose of Januvia is 50 mg once daily.For patients combivent rxlist with severe renal impairment (eGFR less than 30 mL/min/1.73 m 2) or with end-stage renal disease (ESRD) amaryl m requiring hemodialysis or peritoneal dialysis, the januvia renal impairment dose of.73 m 2 to less than 45 mL/min/1.73 m 2: 50 mg PO qDay; eGFR 30 mL/min/1.A januvia renal impairment dosage adjustment is recommended in patients with moderate or severe renal impairment and in patients with end-stage renal disease requiring hemodialysis or peritoneal dialysis.

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