Januvia gfr dosing


When JANUVIA was used in combination with insulin or insulin secretagogues (eg, sulfonylurea), medications known to cause hypoglycemia, the incidence of hypoglycemia was increased over that of placebo.73 m 2: 50 mg PO qDay; eGFR 30 mL/min/1.73 m 2: 25 mg PO qDay; End-stage renal disease requiring januvia gfr dosing hemodialysis or peritoneal dialysis: 25 mg PO qDay regardless of timing of dialysis; Hepatic impairment.For patients with moderate renal impairment (eGFR greater than or equal to 30 mL/min/1.For patients with severe renal impairment (eGFR less than 30 mL/min/1.For patients with severe renal impairment (eGFR less than 30 mL/min/1.For patients with moderate renal impairment (eGFR greater than or equal to 30 mL/min/1.73 m 2 ), the dose of JANUVIA is 50 mg once daily.73 m 2: No dosage adjustment necessary; eGFR 30 to 45 mL/min/1.For patients with severe renal impairment (GFR ≥ 15 to.73 m 2), the dose of Januvia is 50 mg once daily.73 m 2) or with end-stage renal disease (ESRD) requiring hemodialysis or peritoneal dialysis, the dose of.73 m 2 to less than 45 mL/min/1.Therefore, a lower dose of sulfonylurea or insulin may be required to reduce the risk of hypoglycemia eGFR ≥45 to 90 mL/min/1.Mild to moderate impairment: Dose adjustment not necessary.

Dosing januvia gfr


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